ChemInform Abstract: Sulfoxide-Mediated Diastereoselective Michael Additions. New Enantioselective Synthesis of C-4 Substituted 2-Pyroaminoadipic Acids

Autor:	Alfonso de Dios, Hassan Acherki, Carlos Alvarez-Ibarra, Alicia Barrasa
Rok vydání:	2010
Předmět:	chemistry.chemical_compound chemistry Scope (project management) Enantioselective synthesis Sulfoxide General Medicine Combinatorial chemistry Conjugate
Zdroj:	ChemInform. 30
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199941137
Popis:	Diastereoselective reactions of suitably functionalized homochiral β-iminosulfoxides with Michael acceptors provide a new and efficient route for the asymmetric synthesis of C-4 substituted 2-pyroaminoadipates. Extension of the scope of the sulfoxide-mediated aza-enolate conjugate addition (Hua's reaction) has also been explored.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8a44a9ebb8ae417af9ed0e83e8510ad5 https://doi.org/10.1002/chin.199941137 Zobrazit plný text záznamu Plný text