Associations between injecting illicit drugs into the femoral vein and deep vein thrombosis: A case control study

Autor: Victoria Allgar, Charlotte N. E. Tompkins, Nat M. J. Wright
Rok vydání: 2015
Předmět:
Zdroj: Drug and Alcohol Review. 35:605-610
ISSN: 0959-5236
DOI: 10.1111/dar.12359
Popis: Introduction and Aims Injecting drug use is a risk factor for deep vein thrombosis (DVT), and people who inject drugs commonly report injecting into the femoral vein. However, it is unclear whether the act of inserting a needle into the femoral vein or the pharmacodynamic properties of the injected drug increases DVT risk. We aimed to quantify the strength of association between injecting illicit drugs into the femoral vein and the odds of acquiring ileo-femoral DVT. Design and Methods We used case control methodology. The study took place in Leeds, UK. A total of 313 people who inject drugs (112 ‘cases’ with a diagnosis of DVT from hospital accident and emergency departments and 201 ‘controls’ with no DVT from needle exchanges) completed a questionnaire about their drug use and administration routes. Results The act of injecting into the femoral vein was strongly associated with DVT (χ2(1) = 53.453, P
Databáze: OpenAIRE