(E)-N-(pyren-1-ylmethylene)benzenamine: efficient promoter for additive-free palladium catalyzed aerobic oxidative coupling of arylboronic acids and terminal alkynes
| Autor: | Rupesh Narayana Prabhu, Jagadeesan Lakshmipraba, Victor Violet Dhayabaran |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Chemistry
General Chemical Engineering Substrate (chemistry) Sonogashira coupling chemistry.chemical_element 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Biochemistry Medicinal chemistry Industrial and Manufacturing Engineering Coupling reaction 0104 chemical sciences Catalysis Solvent Yield (chemistry) Materials Chemistry Oxidative coupling of methane 0210 nano-technology Palladium |
| Zdroj: | Chemical Papers. 74:3661-3669 |
| ISSN: | 1336-9075 2585-7290 |
| Popis: | A highly productive protocol for the synthesis of internal alkynes by the carbon–carbon cross-coupling reactions of electronically different arylboronic acids with substituted phenylacetylenes was described by employing (E)-N-(pyren-1-ylmethylene)benzenamine with Pd(OAc)2. The influence of reaction parameters such as solvent, base and reaction temperature in this carbon–carbon cross-coupling reaction was also investigated. The substrate scope could be expanded to electron-poor alkynes, for which the conventional Sonogashira reaction gives poor yields. Moderate to excellent yield was obtained in the oxidative Sonogashira-type coupling reaction. |
| Databáze: | OpenAIRE |
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