Matrix-assisted laser desorption/ionization by using femtosecond laser pulses in the near-infrared wavelength regime
| Autor: | Albrecht Lindinger, Ludger Wöste, Jörg M. Wichmann, C. Lupulescu |
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| Rok vydání: | 2009 |
| Předmět: |
Matrix-assisted laser desorption electrospray ionization
business.industry Chemistry Organic Chemistry Far-infrared laser Analytical chemistry Physics::Optics Laser Quantitative Biology::Genomics Soft laser desorption Analytical Chemistry Atmospheric-pressure laser ionization law.invention X-ray laser Matrix-assisted laser desorption/ionization law Femtosecond Physics::Atomic and Molecular Clusters Optoelectronics Physics::Atomic Physics business Spectroscopy |
| Zdroj: | Rapid Communications in Mass Spectrometry. 23:1105-1108 |
| ISSN: | 0951-4198 |
| DOI: | 10.1002/rcm.3974 |
| Popis: | We observe a substantial matrix-assisted laser desorption/ionization (MALDI) signal when irradiating femtosecond laser pulses in the near-infrared spectral range centered around 800 nm and using standard MALDI matrices with absorption bands in the ultraviolet (UV) regime. The laser pulse energy dependence of this novel phenomenon is investigated in comparison with MALDI with near-UV laser pulses. Our observations show that multiphoton absorption/ionization could be a major issue among the MALDI processes when the sample is irradiated with ultra-short laser pulses. |
| Databáze: | OpenAIRE |
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