Study of enzymatic G6P synthesis using polymer-bound ATP in membrane reactors
| Autor: | Wael Abdelmoez, Kosaku Ishimi, Haruo Ishikawa |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
chemistry.chemical_classification
Environmental Engineering Plug flow Chromatography biology Membrane reactor General Chemical Engineering Diffusion technology industry and agriculture Continuous stirred-tank reactor Polymer equipment and supplies complex mixtures Cofactor Enzyme catalysis law.invention chemistry Chemical engineering law biology.protein Filtration Biotechnology |
| Zdroj: | AIChE Journal. 52:683-691 |
| ISSN: | 1547-5905 0001-1541 |
| DOI: | 10.1002/aic.10649 |
| Popis: | The performance of membrane reactors, in which the enzymatic synthesis of glucose 6-phosphate from glucose and polymer-bound cofactor ATP with simultaneous regeneration of polymer-bound ATP from polymer-bound ADP and acetyl phosphate are performed, was analyzed theoretically. Simplified and realistic models for two different membrane reactors, a plug-flow-type membrane reactor (PFMR) in a diffusion mode and a continuous stirred tank reactor-type membrane reactor (CSTMR) in a filtration mode, were presented and compared theoretically. The results showed that the reactor performance mainly depends on the operating conditions and that, in most cases, the PFMR in a diffusion mode was found to be superior to the CSTR in a filtration mode. This study provides useful information for selecting and optimizing of the reactor for enzymatic reactions requiring cofactors. |
| Databáze: | OpenAIRE |
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