| Popis: |
The interferons (IFN) are a family of proteins secreted by mammalian cells in response to various inducers (Baglioni 1979; Revel 1979; Stewart 1979; Friedman 1981; Pestka 1981; Torrence 1982; Sehgal et al. 1983). The interferons are divided into three different types α, β, γ, whereby each class can be summarized from different species for which a separate IFN gene is coded. The interferons are pleotropic modifiers of cell functions as seen from their antiviral properties (Sehgal et al. 1983), the inhibition of cell growth, the inhibition of tumor cell proliferation, their augmentation of natural killer (NK) activity, the modulation of immune response, the interaction of nuclear formation and the delay of cells entering into S-phase of the cell cycle (Suhadolnik et al. 1983). |
