| Autor: |
Dashyant Dhanak, Paul Bury, G. Hareau, Philip J. Kocienski |
| Rok vydání: |
1994 |
| Předmět: |
|
| Zdroj: |
Tetrahedron. 50:8793-8808 |
| ISSN: |
0040-4020 |
| Popis: |
Two approaches to the sesterterpenoid phospholipase A2 inhibitors seco--manoalide (3) and manoalide (1) are described based on carbometallation of propargylic alcohols to generate the functionalised C6–C7 trisubstituted alkene. Both syntheses also deploy the photooxidation of a furan in order to generate a 4-substituted-5-hydroxy-2(5H)-furanone moiety. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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