Symptoms of Anxiety and Depression as Risk Factors for Development of Asthma

Autor: James Lando, Jacob J. Feldman, Bruce S. Jonas, Diane K. Wagener
Rok vydání: 1999
Předmět:
Zdroj: Journal of Applied Biobehavioral Research. 4:91-110
ISSN: 1751-9861
1071-2089
DOI: 10.1111/j.1751-9861.1999.tb00058.x
Popis: To test the hypothesis that symptoms of anxiety and depression are associated with increased risk of developing asthma, a population-based cohort of 5,23! baseline and non-asthmatic persons aged 25 to 74 was followed for 13 years. The association between asthma incidence and anxiety and depression was analyzed using Cox proportional hazards regression. For nonsmokers and persons without respiratory symptoms or predicted-to-observed FEVI ratio less than 65% (FEV1 < 65%), high levels of anxiety and depression remained independent predictors of asthma. The effects of anxiety and depression were particularly strong among nonsmokers without baseline respiratory symptoms or FEVI < 65%. We hypothesize that the baseline presence of strong risk factors such as smoking, respiratory symptoms, or FEV1 < 65% may obscure the effects of anxiety and depression symptomatology on the subsequent development of asthma. These analyses point out the need to move toward more sophisticated stratified models in the study of psychological factors and asthma.
Databáze: OpenAIRE