Molecular cloning of an Actinobacillus pleuropneumoniae outer membrane lipoprotein (Oml A) from serotype 5a

Autor:	Eiji Ooishi, Nobuyuki Terakado, Tooru Kawai, Akira Taneno, Hiroya Ito, Tatsuji Okabe, Ikuo Uchida, Tsutomu Sekizaki
Rok vydání:	1995
Předmět:	Serotype biology Strain (chemistry) Sequence analysis Molecular cloning biology.organism_classification Microbiology Molecular biology Infectious Diseases Bacterial outer membrane Actinobacillus pleuropneumoniae Peptide sequence Southern blot
Zdroj:	Microbial Pathogenesis. 18:29-36
ISSN:	0882-4010
DOI:	10.1016/s0882-4010(05)80010-5
Popis:	The gene encoding an outer membrane lipoprotein (OmIA) was cloned from Actinobacillus pleuropneumoniae strain NG-8 (serotype 5a). The deduced amino acid sequence of OmIA from strain NG-8 showed 61% identity to the OmIA from serotype 1 strain, which confers protective immunity to pigs. Southern blot analysis showed the presence of a sequence highly homologous to the omIA gene of strain NG-8 in strains of serotype 5a, 5b and 10. A specific serum against OmIA of NG-8 also detected a homologous protein in the strains of these serotypes. These data shows the presence of antigenic variability among A. pleuropneumoniae OmIA proteins.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::89d471187a91d343d39784d2645d2eee https://doi.org/10.1016/s0882-4010(05)80010-5 Zobrazit plný text záznamu Full Text from ScienceDirect