Efficient syntheses of four chiral phenylcyclopropanes

Autor:	Stephanie R. Singer, John E. Baldwin
Rok vydání:	2008
Předmět:	Chemistry Organic Chemistry Organic chemistry General Chemistry Enantiomeric excess Catalysis
Zdroj:	Canadian Journal of Chemistry. 86:395-400
ISSN:	1480-3291 0008-4042
Popis:	An efficient four-step synthetic route from each of four crystalline isotopically labeled (1R)-menthyl (1S,2S)-(+)-2-phenylcyclopropanecarboxyates of better than 99% enantiomeric excess has provided multi-gram quantities of the corresponding chiral phenylcyclopropanes. The key transformation involved a bis[1,3-bis(diphenylphosphino)propane]rhodium chloride that catalyzed a highly stereoselective decarbonylation of a trans-2-phenylcyclopropanecarboxaldehyde.Key words: cyclopropanes chiral thanks to isotopic substituents, catalytic decarbonylations of cyclopropanecarboxaldehydes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::89ca4dc70f9fd8c8ed740d9a3c4f1b4d https://doi.org/10.1139/v08-033 Zobrazit plný text záznamu Plný text ve formátu PDF