Anaplasma marginaleYucatan (Mexico) Strain

Autor:	Ramón Aboytes Torres, Germinal Jorge Cantó Alarcón, Jesús Francisco Preciado de la Torre, Miguel Ángel García Ortiz, Rodrigo Rosario Cruz, Juan Alberto Ramos Aragón, Sergio Darío Rodríguez Camarillo, Edmundo Enrique Rojas Ramírez
Rok vydání:	2008
Předmět:	Attenuated vaccine Inoculation General Neuroscience Strain (biology) Virulence Heterologous Biology Virology General Biochemistry Genetics and Molecular Biology Microbiology Vaccine strain History and Philosophy of Science Immunization Anaplasma marginale
Zdroj:	Annals of the New York Academy of Sciences. 1149:98-102
ISSN:	1749-6632 0077-8923
DOI:	10.1196/annals.1428.067
Popis:	Anaplasma marginale Yucatan strain was found to have low virulence in cattle. We studied the virulence of this isolate by experimental inoculation of 113 susceptible cattle at increasing doses, after which only one animal required treatment for clinical disease. Subsequently, 104 cattle received a live vaccine of this strain by inoculation, which induced immunoprotection after heterologous challenged exposure with a different A. marginale isolate. In this study 14% of the immunized cattle required treatment as compared with the control nonimmunized cattle, in which 56% required treatment. The A. marginale vaccine strains used for the immunization studies had MSP1a variable regions that were different from those used for the challenge exposure.
Databáze:	OpenAIRE
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