Intra-articular Corticosteroid Injections in the Hip and Knee: Perhaps Not as Safe as We Thought?
| Autor: | Ali Guermazi, Michel D. Crema, Luis E. Diaz, Akira M. Murakami, Andrew J. Kompel, Frank W. Roemer |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
musculoskeletal diseases
medicine.medical_specialty business.industry medicine.drug_class Retrospective cohort study Osteoarthritis medicine.disease Additional research 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Intra articular 030220 oncology & carcinogenesis medicine Insufficiency fracture Joint disorder Corticosteroid Radiology Nuclear Medicine and imaging In patient Intensive care medicine business |
| Zdroj: | Radiology. 293:656-663 |
| ISSN: | 1527-1315 0033-8419 |
| Popis: | Osteoarthritis (OA) of the hip and knee is among the most common joint disorders. Intra-articular corticosteroid (IACS) injections are frequently performed to treat OA and other joint-related pain syndromes; however, there is conflicting evidence on their potential benefit. There is a lack of prospective and large retrospective studies evaluating potential joint findings, including increased risk for accelerated OA progression or adverse joint events, after treatment with IACS injection. Four main adverse joint findings have been structurally observed in patients after IACS injections: accelerated OA progression, subchondral insufficiency fracture, complications of osteonecrosis, and rapid joint destruction, including bone loss. Physicians, including radiologists, should be familiar with imaging findings and patient characteristics that may help them identify potential joints at risk for such events. The purpose of this report is to review the existing literature, describe observed adverse joint events after IACS injections, and provide an outlook on how this may affect clinical practice. Additional research endeavors are urgently needed to better understand and identify risk factors prior to intervention and to detect adverse joint events after injection as early as possible to prevent or minimize complications. |
| Databáze: | OpenAIRE |
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