A multiparous pregnant woman receiving chemotherapy for breast cancer

Autor:	N. Ramu, Yaakov Cass, B. Uziely, T. Peretz, N. Heching, Y. Pappo
Rok vydání:	1995
Předmět:	Gynecology Pregnancy medicine.medical_specialty Chemotherapy Obstetrics business.industry medicine.medical_treatment Cancer medicine.disease Malignancy Breast cancer Oncology medicine Carcinoma Pharmacology (medical) Doxorubicin business Cause of death medicine.drug
Zdroj:	Journal of Oncology Pharmacy Practice. 1:37-39
ISSN:	1477-092X 1078-1552
DOI:	10.1177/107815529500100307
Popis:	Cancer is the second leading cause of death in women during the childbearing years. Breast can cer is the most common malignancy presenting during pregnancy and lactation. Treatment with antineoplastic agents in this group of patients is problematic due to their potential teratogenicity. A case report is presented of a pregnant woman who received neo-adjuvant chemotherapy for locally advanced carcinoma of the breast. The patient received a total of four courses of cyclophospha mide, doxorubicin and 5-fluorouracil, before deliv ery of a child healthy in all systems. We discuss the use of cytotoxic drugs during pregnancy and indi cate some of the dilemas facing the treating physi cian. The authors join in the call for the establish ment of an international registry of children born to mothers who receive cytotoxic drugs during pregnancy.
Databáze:	OpenAIRE
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