| Autor: |
null Winly, Fabiola Supit, Ari Andayani, Ni Made Ari Suryathi |
| Rok vydání: |
2023 |
| Zdroj: |
Vision Science and Eye Health Journal. 2:34-40 |
| ISSN: |
2809-218X |
| Popis: |
Introduction: The primary treatment in proliferative diabetic retinopathy (PDR) is vitrectomy; however, direct intervention to the dense proliferative fibrovascular membrane may lead to massive hemorrhage obscuring the surgery process. Purpose: to review the use of anti-vascular endothelial growth factor (VEGF) as an adjuvant therapy before pars plana vitrectomy in PDR cases. Review: Anti-VEGF has been proposed as an adjuvant preceding the vitrectomy to lower intraoperative and post-operative complications. On the other hand, it could increase fibrosis which triggers tractional retinal detachment (TRD) in PDR cases. Conclusion: Intervals of five to ten days are considered the most ideal between anti-VEGF injection and pars plana vitrectomy (PPV) surgery in which the adjuvant therapy has made neovascularization regression and before the occurrence of fibrovascular contractions. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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