Acute heart failure as a result of granulomatous myocarditis: case report on a patient with metastatic melanoma treated with dabrafenib and trametinib
| Autor: | Julia K. Winkler, E. Ellert, Esther Herpel, Alexander Enk, U.M. Martens, Jessica C. Hassel, Kristina Buder-Bakhaya |
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| Rok vydání: | 2017 |
| Předmět: |
Trametinib
Myocarditis business.industry medicine.medical_treatment Melanoma Dabrafenib Dermatology 030204 cardiovascular system & hematology medicine.disease Targeted therapy 03 medical and health sciences 0302 clinical medicine Infectious Diseases Immune system Heart failure Immunology medicine Cancer research 030212 general & internal medicine skin and connective tissue diseases business Protein kinase A neoplasms medicine.drug |
| Zdroj: | Journal of the European Academy of Dermatology and Venereology. 32:e31-e32 |
| ISSN: | 0926-9959 |
| DOI: | 10.1111/jdv.14467 |
| Popis: | Treatment options for metastatic melanoma have changed substantially in recent years. Targeting immune checkpoints has improved prognosis of melanoma patients. For melanomas harboring BRAF mutations, inhibition of the mitogen-activated protein kinase pathway is a promising therapeutic option. Combined BRAF and MEK inhibition improves progression-free and overall survival. This article is protected by copyright. All rights reserved. |
| Databáze: | OpenAIRE |
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