Effect of hydrolipophilic equilibrium of the muramyl dipeptide derivatives on their internalization and interactions in biological membranes

Autor: O. V. Kalyuzhin, B. B. Fuks
Rok vydání: 1996
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 122:1219-1221
ISSN: 1573-8221
0007-4888
Popis: The interaction between two homologous muramyl dipeptide derivatives (β-heptylglycoside and β-hexadecylglycoside) and model membranes and internalization of these derivatives into K562 human erythroleukemia cells are studied. It is suggested that the difference in the interaction of these homologs with model membranes and in their immunomodulating activities result from different hydrolipophilic balance of these perorations.
Databáze: OpenAIRE