| Autor: | E. M. Volkov, V. N. Frosin, L. F. Nurullin |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Membrane potential
medicine.medical_specialty Carbachol General Medicine Biology Resting potential General Biochemistry Genetics and Molecular Biology Atropine chemistry.chemical_compound Endocrinology chemistry Internal medicine medicine Myocyte Cholinergic Hexamethonium medicine.drug Acetylcholine receptor |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 131:397-398 |
| ISSN: | 0007-4888 |
| DOI: | 10.1023/a:1017980909248 |
| Popis: | Carbachol in a concentration of 5x10(-8) mol/liter does not hyperpolarize, and in a concentration of 5x10(-6) mol/liter depolarizes the membrane of somatic muscle cell in earthworm. d-tubocurarine, alpha-bungarotoxin, atropine, and hexamethonium added to the incubation medium did not abolish the carbachol-induced decrease in resting membrane potential. Each of these drugs alone had no effect on resting membrane potential in muscle cells. Presumably, the acetylcholine-sensitive receptor-channel membrane complex in earthworm muscle cell differs from acetylcholine receptor in skeletal muscle fibers and peripheral neurons of vertebrates. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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