Multifocal Malignant Lymphoma of the Breast

Autor:	Ayca Tan, Sehnaz Emil Sayhan, Nurten Bozlak, Deniz Tunçel, Elmas Ozgun, Aynur Albayrak
Rok vydání:	2013
Předmět:	CD20 Pathology medicine.medical_specialty medicine.diagnostic_test biology business.industry CD68 CD34 medicine.disease Lymphoma Lesion immune system diseases hemic and lymphatic diseases Biopsy medicine biology.protein Immunohistochemistry Mammography medicine.symptom business
Zdroj:	Open Journal of Pathology. :127-130
ISSN:	2164-6783 2164-6775
DOI:	10.4236/ojpathology.2013.33023
Popis:	Primary non-Hodgkin’s lymphomas is an uncommon disease representing approximately 0.13% of all reported malignant mammary neoplasms. Clinically they are mainly observed as solitary lesions, but may also be seen as multiple foci. Herein, we present a very rare case with the diagnosis of multifocal malignant lymphoma of the breast. Case: A 56-year-old-female patient with a right palpable breast mass admitted to the hospital. Mammography and ultrasonography findings showed two different foci of hypoechoic solid mass forming lesion in the right breast. Excisional biopsy has been performed. In the histopathological evaluation, both lesions demonstrated foci of necrosis; mitotically active tumor cells with large nucleus and prominent nucleoli. The immunohistochemical analysis revealed diffuse LCA, CD20, CD43, focal CD68 positivity while pancytokeratin, EMA, CD34, SMA were negative. The case was diagnosed as Diffuse Large B-cell Lymphoma. We report a very rare case with a diagnosis of multifocal primary non-Hodgkin’s lymphoma of the breast.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::89639b37e22ee74862f1b8ead28e8030 https://doi.org/10.4236/ojpathology.2013.33023 Zobrazit plný text záznamu