Determinants of Quality of Life in Spanish outpatients with schizophrenia spectrum disorders
| Autor: | J.I. Arraras, M. Martin, S. Iribarren, Berta Ibáñez, I. Basterra, N. Pereda |
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| Rok vydání: | 2018 |
| Předmět: |
Psychosis
Multivariate statistics Univariate analysis business.industry Univariate medicine.disease humanities 030227 psychiatry 03 medical and health sciences Psychiatry and Mental health 0302 clinical medicine Quality of life Schizophrenia Medicine business 030217 neurology & neurosurgery Depression (differential diagnoses) Clinical psychology Schizophrenia spectrum |
| Zdroj: | The European Journal of Psychiatry. 32:113-121 |
| ISSN: | 0213-6163 |
| DOI: | 10.1016/j.ejpsy.2017.11.001 |
| Popis: | Background and objectives Quality of Life (QoL) studies of patients with psychosis living in the community and of its determinants can help to improve support offered to patients. This study evaluates QoL in Spanish outpatients with schizophrenia spectrum disorders and attempts to identify the QoL determinants. Methods Sixty-one patients with schizophrenia or schizoaffective disorders and stable disease, completed the generic WHOQOL-BREF, EUROQOL-5D-5L and the specific SQLS-R4 QoL scales and the SCIP (cognitive impairment), SAI-E (insight), and Calgary (depression) scales. SANS (Scales for Assessment of Negative Symptoms) and SAPS (Scales for Assessment of Positive Symptoms) and selected items from the QOLI-BV were also evaluated. Frequencies in the clinical, demographic and QoL variables were studied. Univariate and multivariate regression models were fitted to assess how clinical and demographic characteristics influence subjective QoL. Multivariate regression models were fitted with all explanatory variables found to be significant in univariate analysis. Results Mean QoL scores were 58.8 in EUROQOL-health and 0.8 in EUROQOL-value, and ranged between 49.2 and 62.7 in WHOQOL-BREF and between 38.9 and 43.3 (QoL limitations) in SQLS-R4. Negative symptoms and depression were significantly related to the nine QoL areas studied. Age, gender, social activities, employment status, time since diagnosis, and insight were also related to QoL. The percentage of variance in the QoL areas explained in multivariate regression models ranged from 25 to 56%. Conclusion QoL was moderate in this sample of Spanish schizophrenia spectrum outpatients. Sociodemographic and clinical factors were found to be determinants of QoL. These patients could benefit from multidisciplinary treatment to improve their QoL. |
| Databáze: | OpenAIRE |
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