Associations of Disease Activity and Socio-demographic Factors with Activity and Participation of Patients with Rheumatoid Arthritis – Results of a Cross-sectional Study
| Autor: | S. Elsner, H. Kuhlow, S. R. Schwarzkopf, E. Grill, K.-L. Resch |
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| Rok vydání: | 2015 |
| Předmět: |
Variance inflation factor
education.field_of_study medicine.medical_specialty Rehabilitation Cross-sectional study business.industry medicine.medical_treatment Population Physical Therapy Sports Therapy and Rehabilitation medicine.disease Logistic regression Rheumatoid arthritis medicine Physical therapy Outpatient clinic education business Statistic |
| Zdroj: | Physikalische Medizin, Rehabilitationsmedizin, Kurortmedizin. 25:141-147 |
| ISSN: | 1439-085X 0940-6689 |
| Popis: | Purpose: To analyze the associations of disease activity, functioning and socio-demographic factors with activity and participation in patients with RA, and to characterize the RA population of a specialized multiprofessional hospital based outpatient program (HBOP) for RA at baseline focusing on deficits in functioning and disease activity. Material and Methods: In a prospective cross sectional study of a HBOP, baseline assessments of patients referred to an academic outpatient department fulfilling the inclusion criteria were studied. Socio-economic data were assessed with a socio-demographic questionnaire, disease activity with the DAS3, DAS4 and RADAI, disability with the HAQ-DI. For statistical analysis, logistic regression models, non-parametric tests, Hosmer-Lemeshow statistic, Variance Inflation Factor and Box-Tidwell tests were used. Results: Data of 122 consecutive patients (mean age 56 years; 79% female; mean disease duration 10 years) were analyzed. Disease activity (DAS3, DAS4, RADAI) was positively correlated with disability (HAQ-DI) (Spearman correlation coefficients 0.53, 0.56, 0.53; DAS3 and DAS4 0.97). RADAI was significantly associated with HAQ-DI subscores (dressing: OR=1.71, 95% CI 1.32–2.23; gripping: OR=1.67, 95% CI 1.29–2.16). Adjusted for age at diagnosis, sex, education and household size DAS3 and HAQ-DI showed a significant association (OR=2.58, 95% CI 1.71–3.88), similar results were observed for DAS4 and RADAI; and RADAI and gripping and dressing (OR=1.85, 95% CI 1.42–2.40). Conclusions: Disease activity was positively related with disability and participation. Fine motor skills of the hand were significantly associated with the HAQ-DI. Socio-demographic data seem to be associated with disability. |
| Databáze: | OpenAIRE |
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