Consumption of enzyme resistant starch and cholesterol metabolism in normo- and hypercholesterolemic rats
| Autor: | R. De Schrijver, K. Vanhoof |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
medicine.medical_specialty
Nutrition and Dietetics food.ingredient Bile acid Cholesterol Diet therapy medicine.drug_class Endocrinology Diabetes and Metabolism Inulin food and beverages Biology Excretion Coprostanol chemistry.chemical_compound Endocrinology food chemistry Amylose Internal medicine medicine Resistant starch |
| Zdroj: | Nutrition Research. 17:1331-1340 |
| ISSN: | 0271-5317 |
| DOI: | 10.1016/s0271-5317(97)00117-6 |
| Popis: | The influence of raw and retrograded high amylose corn starch on cholesterol metabolism in normo- as well as hypercholesterolemic rats was studied. No effect on cholesterol metabolism was observed in normocholesterolemic rats. On the contrary, in hypercholesterolemic animals plasma free and total cholesterol concentrations were significantly lower when enzyme resistant starch was fed. Liver cholesterol concentrations were significantly decreased in rats given the hypercholesterolemic diet supplemented with retrograded high amylose corn starch. Total fecal bile acid excretion and bile acid spectrum were not changed by enzyme resistant starch consumption. Plasma total cholesterol concentrations showed a significantly negative correlation with fecal coprostanol excretion in hypercholesterolemic rats. However, there is no evidence that coprostanol is the only factor responsible for the observed hypocholesterolemic effect of enzyme resistant starch in cholesterol fed rats. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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