Neurotoxicity of Combined Radiation and Chemotherapy
Autor: | Jerome B. Posner, Lisa M. DeAngelis, Roland Gerritsen van der Hoop |
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Rok vydání: | 1990 |
Předmět: |
Oncology
Cerebral atrophy medicine.medical_specialty Chemotherapy Childhood leukemia business.industry medicine.medical_treatment Central nervous system Neurotoxicity medicine.disease Radiation therapy medicine.anatomical_structure Internal medicine Acute lymphocytic leukemia medicine Methotrexate business medicine.drug |
Zdroj: | Neurological Adverse Reactions to Anticancer Drugs ISBN: 9783642761447 |
Popis: | Most observers believe that when radiation therapy to the central nervous system is combined with either systemic or intrathecal chemotherapy, neurotoxicity is more likely to result than when either of these modalities is used alone. The evidence for such synergism is best established for methotrexate but other chemotherapeutic agents have also been implicated (Table 1). |
Databáze: | OpenAIRE |
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