Physical training prevents oxidative stress in L-NAME-induced hypertension rats

Autor: Luiz Fernando Freire Royes, Caroline Curry Martins, Amanda Maino Fiorenza, Jessié Martins Gutierres, Fernando da Silva Fiorin, Maria Rosa Chitolina Schetinger, Fabiano B. Carvalho, Verônica Souza Paiva Castro, Daniela Zanini, Andréia Machado Cardoso, Roberta Schmatz, Jeferson Ferraz Goularte, Fátima Husein Abdalla, Naiara Stefanello, Margarete Dulce Bagatini, Vera Maria Morsch, Cinthia M. Mazzanti, Adriane Belló-Klein, Jonas Daci da Silva Serres
Rok vydání: 2012
Předmět:
Zdroj: Cell Biochemistry and Function. 31:136-151
ISSN: 0263-6484
DOI: 10.1002/cbf.2868
Popis: The present study investigated the effects of a 6-week swimming training on blood pressure, nitric oxide (NO) levels and oxidative stress parameters such as protein and lipid oxidation, antioxidant enzyme activity and endogenous non-enzymatic antioxidant content in kidney and circulating fluids, as well as on serum biochemical parameters (cholesterol, triglycerides, urea and creatinine) from Nω-nitro-L-arginine methyl ester hydrochloride (L-NAME)-induced hypertension treated rats. Animals were divided into four groups (n = 10): Control, Exercise, L-NAME and Exercise L-NAME. Results showed that exercise prevented a decrease in NO levels in hypertensive rats (P
Databáze: OpenAIRE