Fast-to-slow shift of muscle fiber-type composition by dietary apple polyphenols in rats: Impact of the low-dose supplementation

Autor: Yoshihide Ikeuchi, Ryuichi Tatsumi, Hideaki Ohtsubo, Yusuke Komiya, Wataru Mizunoya, Mariko Akahoshi, Toshiaki Waga, Judy E. Anderson, Mai Khoi Q. Do, Koichi Nakazato, Hideo Miyahara, Takahiro Suzuki, Mulan Qahar, Shinpei Okamoto
Rok vydání: 2016
Předmět:
Zdroj: Animal Science Journal. 88:489-499
ISSN: 1344-3941
Popis: Our previous studies demonstrated that an 8-week intake of 5% (w/w) apple polyphenol (APP) in the diet improves muscle endurance of young-adult rats. In order to identify a lower limit of the dietary contribution of APP to the effect, the experiments were designed for lower-dose supplementation (8-week feeding of 0.5% APP in AIN-93G diet) to 12-week-old male Sprague-Dawley rats. Results clearly showed that the 0.5% APP diet significantly up-regulates slower myosin-heavy-chain (MyHC) isoform ratios (IIx and IIa relative to total MyHC) and myoglobin expression in lower hind-limb muscles examined (P
Databáze: OpenAIRE