Autologous transplantation of CD133+ BM-derived stem cells as a therapeutic option for dilatative cardiomyopathy
| Autor: | E.R. Burchardt, Andreas Borowski, T. Voelkel, R. Marktanner, Christoph Piechaczek, Ludger Wilhelm Poll, Marcus Stockschlaeder, HM Klein, A Ghodsizad, Christoph Sucker, M. R. Mohammad Hasani, Arjang Ruhparwar, Volker R. Stoldt, Emmeran Gams, I. Vshivkov |
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| Rok vydání: | 2006 |
| Předmět: |
Cancer Research
Transplantation medicine.medical_specialty business.industry medicine.medical_treatment Immunology Cardiomyopathy Cell Biology Stem-cell therapy medicine.disease Surgery medicine.anatomical_structure Cell transplantation Oncology Ventricle Internal medicine Heart failure medicine Cardiology Immunology and Allergy Autologous transplantation Stem cell Cardiac magnetic resonance business Genetics (clinical) |
| Zdroj: | Cytotherapy. 8:308-310 |
| ISSN: | 1465-3249 |
| Popis: | We report the case of a 58-year-old man with end-stage non-ischemic cardiomyopathy. Baseline transthoracic echocardiography (TTE) and cardiac magnetic resonance (cMRI) revealed a markedly depressed left ventricle systolic function. He underwent autologous CD133+ BM-derived cell transplantation through a minimally invasive approach. During surgery 19×106 BM-derived stem cells were injected by the transepimyocardial route. Six months after the operation TTE and cMRI showed a clear improvement in left ventricular contractility. |
| Databáze: | OpenAIRE |
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