Divergent Thio/Selenolactonization of Styrene-Type Carboxylic Acids and Amides: Synthesis of Chalcogenated Isobenzofuran-1 (3H)-ones and Isochroman-1-ones

Autor:	Kang Zhao, Yunfei Du, Jingran Zhang, Kommuru Goutham, Yaxin Ouyang
Rok vydání:	2022
Předmět:	Organic Chemistry
Zdroj:	Synlett. 33:1266-1272
ISSN:	1437-2096 0936-5214
Popis:	A divergent synthesis of isobenzofuran-1(3H)-one and 3,4-dihydroisochroman-1-one derivatives has been realized through the reaction of o-alkenyl benzoic acids/amides with PhICl2 and diphenyl disulfides/diselenides. Depending on the substitution type of the o-alkenyl benzoic acid or amide, this metal-free intramolecular oxychalcogenation approach regioselectively affords isobenzofuran-1(3H)-ones or 3,4-dihydroisochroman-1-ones through 5-exo-trig or 6-endo-trig cyclization processes, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::89177bae8b652c97c3be1492dd94c6ae https://doi.org/10.1055/a-1827-6915 Zobrazit plný text záznamu