Asymmetric synthesis of 2-substituted 4-chromanones using enzyme-catalyzed reactions
Autor: | Masashi Kawasaki, Chiho Hiraoka, Kanako Katayama, Naoki Toyooka, Akihisa Inoue, Akira Tanaka, Hiroko Kakuda, Michimasa Goto, Yuka Asano, Tadashi Kometani |
---|---|
Rok vydání: | 2008 |
Předmět: | |
Zdroj: | Journal of Molecular Catalysis B: Enzymatic. 54:93-102 |
ISSN: | 1381-1177 |
DOI: | 10.1016/j.molcatb.2007.12.022 |
Popis: | 2-Substituted 4-chromanones were synthesized in their optically active forms. The chiral intermediates were obtained via lipase-catalyzed enantioselective reactions. Lipase and esterase were also used for the hydrolysis of ester moieties of the precursors of the target compounds under mild conditions. |
Databáze: | OpenAIRE |
Externí odkaz: |