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Background: The clinical features of coronavirus disease (COVID-19) in pregnant women remain unknown. We describe the clinical characteristics and outcomes of pregnant women with COVID-19 in Japan. Methods: A nationwide survey of pregnant women with COVID-19 was conducted in July 2020. A questionnaire was sent to all institutions offering maternity services in Japan. Information regarding maternal characteristics, epidemiological, clinical, treatment, and perinatal outcomes were extracted. Findings: Responses from 1418 institutions were assessed (65% of all delivery institutions in Japan). Seventy-two pregnant women were reported to be diagnosed with COVID-19 between January and June 2020. The positive rate of the universal screening test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for asymptomatic pregnant women was 0·03% (2/7428). The most common route of infection was familial (57%). Fifty-eight pregnant women with COVID-19 were symptomatic, of which 5 (8·6%) had a severe infection. There was one death, a tourist. Severe respiratory symptoms, oxygen administration, and pneumonia were frequently reported in the 3rd trimester and postpartum period compared to early pregnancy (22·2% vs. 2·5% (p=0·03), 38·9% vs. 7·5% (p=0·01), and 50·0% vs. 7·5% (p |
