AB0793 Facet joint disease in patients with axial spondyloarthritis: a retrospective conventional computed tomography study
| Autor: | G. Slobodin, M. Sagiv, T. Khreish, A. Shouval, S. Croitoru, I. Eshed |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Annals of the Rheumatic Diseases. 81:1523.2-1524 |
| ISSN: | 1468-2060 0003-4967 |
| Popis: | BackgroundFacet joints’ (FJ) ankylosis was reported to occur frequently in patients with ankylosing spondylitis (AS). However, a detailed FJ evaluation was not reported in patients over the spectrum of axial spondyloarthritis (AxSpA).ObjectivesTo analyze structural lesions in the FJ of patients with different forms of AxSpA, using computed tomography (CT).MethodsAll available conventional CT studies of the cervical, thoracic, lumbar spine, or studies of the chest or abdomen of patients with AS or non-radiographic AxSpA (nrAxSpA) from a single medical center cohort were analyzed for the presence of erosions, ankylosis, joint-space narrowing, osteophytes, subchondral sclerosis, subchondral cysts and vacuum phenomenon by 2 experienced readers. All patients, as well as age and gender matched control group, who performed conventional CT of the spine for any cause, but did not have a known rheumatic disease, had to be at the age of 50 years or less at the time of the study. The findings were binarically scored as present/absent. Several types of changes could be noted in the same FJ. All FJ findings were compared between groups of AxSpA patients and controls, separately for the cervical, thoracic and lumbar spine. Further, AxSpA patients were subdivided into three groups of which FJ findings were compared: AS patients with (AS+) or without (AS-) syndesmophytes on the cervical or lumbar radiographs, and patients with nrAxSpA as per pelvic radiograph. Fisher’s exact test or Chi-Square test at < http://vassarstats.net >, were used to compare between groups.Results959/666 FJs (49/44 patients) were assessed in the AxSpA/control group patients, respectively. The study group consisted of 16 AS+ patients, 22 AS- patients, and 11 nrAxSpA patients. FJ ankylosis was significantly more prevalent in all spinal segments of the AS + group compared to the two other groups. Erosions were seen almost exclusively in patients with AS. Joint-space narrowing and osteophytes were noted in all segments and all subgroups of AxSpA patients, including those with nrAxSpA.ConclusionFJ involvement is prevalent in all forms of AxSpA, including its non-radiographic form. Facet joints of all spinal segments are involved in AxSpA patientsReferences[1]Jung JY, Kim MY, Hong YS, Park SH, Kang KY. Association between facet joint ankylosis and functional impairment in patients with radiographic axial spondyloarthritis. Seminars in arthritis and rheumatism. 2021; 51(5):1005-1010.[2]Stal R, van Gaalen F, Sepriano A, Braun J, Reijnierse M, van den Berg R, et al. Facet joint ankylosis in r-axSpA: detection and 2-year progression on whole spine low-dose CT and comparison with syndesmophyte progression. Rheumatology. 2020; 59(12):3776-3783.Disclosure of InterestsNone declared |
| Databáze: | OpenAIRE |
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