Subclassification of Localized Leishmania Lymphadenitis in Fine Needle Aspiration Smears
| Autor: | Perikala V. Kumar, Abdollah Moosavi, Habib Noorani, Behnam Abdollahi, Akbar Safaei, Gholam Reza Bedayat, Mehran Karimi |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
education.field_of_study
Pathology medicine.medical_specialty Histology medicine.diagnostic_test business.industry Population General Medicine Plasma cell Pathology and Forensic Medicine medicine.anatomical_structure Fine-needle aspiration Cytopathology Giant cell Medicine Differential diagnosis business education Epithelioid cell Histiocyte |
| Zdroj: | Acta Cytologica. 45:547-554 |
| ISSN: | 1938-2650 0001-5547 |
| DOI: | 10.1159/000327863 |
| Popis: | OBJECTIVE: To describe the cytologic findings of localized Leishmania lymphadenitis arid discuss the differential diagnosis. STUDY DESIGN: The study group consisted of 133 cases. All of them were diagnosed by fine needle aspiration (FNA) study. The ages ranged between 3 and 80 years, 102 were male and 31 female. Seventy lymph nodes were excised. RESULTS: The FNA smears revealed a polymorphic population of cells composed of lymphocytes, histiocytes, giant cells, abnormal plasma cells and tingible body macrophages. Leishman-Donovan (LD) bodies were identified in all cases, but their number differed from case to case. Granulomas, dendritic cells, mast cells and lymphoglandular bodies were identified in a substantial number of cases. Depending upon the presence of characteristic cytologic findings, the cases were divided into five major groups: acute inflammation with giant cells, histiocytic granulomas, epithelioid cell granulomas, plasma cell type and mixed histioplasmacytic type. CONCLUSION: Leishmaniasis is an uncommon cause of cervical lymphadenitis but should be considered in the differential diagnosis of unexplained lymphadenopathy in endemic countries. Demonstration of LD bodies is necessary for the diagnosis of this self-limited condition, for which no treatment is required. |
| Databáze: | OpenAIRE |
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