| Autor: |
Trosala S.C, Basak Durmus, Zeynep Karakas, Yalcinkaya D, Ilknur Tanboga, Guven Y, Ebru Saribeyoglu |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Dentistry. |
| ISSN: |
2161-1122 |
| DOI: |
10.4172/2161-1122.1000158 |
| Popis: |
Aim: Evaluating the efficacy of lactoperoxidase included oral care products for xerostomia in children with cancer undergoing chemotherapy and / or radiotherapy and to present an easy to follow oral care protocol. Design: The study subjects consisted of twenty one pediatric cancer patients (mean age of 11,3±) with either leukemia or lymphoma used lactoperoxidase-system-containing mouth rinse (Biotene ® ) combined with (Biotene ® ) gel or (Biotene®) chewing gum for 3 weeks. Unstimulated saliva samples were collected at the base line and 4 weeks after the usage of the products. They were analyzed for selected biochemical factors and subjective symptoms as intra-oral dryness (xerostomia), eating ability and oral discomfort were graded by visual analogue scale. Results: No major changes occurred in the level of saliva Thiocyanite and Peroxidase activity, but there was a increase in salivary pH and also salivary flow rate was notably higher in groups using Lactoperoxidase products. Changes related to buffering capacity of saliva were also recorded. Conclusion: There is no clearly effective treatment for xerostomia but we have observed in our practice that the use of non-immunologic antimicrobial agents relieves subjective oral symptoms in most xerostomic pediatric patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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