Protecting group release through photoinduced electron transfer: Wavelength control through sensitized irradiation

Autor:	Albert G. Fang, Daniel E. Falvey, Anamitro Banerjee, Kwangjoo Lee, Qing Yu
Rok vydání:	1998
Předmět:	Absorption (pharmacology) Chemistry Organic Chemistry Photodissociation Photochemistry Phenacyl Biochemistry Photoinduced electron transfer Wavelength chemistry.chemical_compound Excited state Drug Discovery Irradiation Protecting group
Zdroj:	Tetrahedron Letters. 39:4635-4638
ISSN:	0040-4039
Popis:	Phenacyl esters (benzoylmethyl esters, PhCOCH2OCOR) release carboxylic acids upon photolysis using photosensitizers that are good one-electron donors in the excited state. Herein it is demonstrated that this procedure can be used to control the wavelength of light required to trigger the release. A variety of sensitizers having different absorption profiles are employed and in each case high isolated yields of carboxylic acids are achieved. It is further demonstrated that this method be extended into the visible (>400 nm) region of the spectrum.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::88eec6a6c9107c921c680680dda39f00 https://doi.org/10.1016/s0040-4039(98)00857-0 Zobrazit plný text záznamu Full Text from ScienceDirect