| Popis: |
Exposure to certain harmful agents through inhalation, chronic skin exposure, or intravenous use may lead to chemical toxicity with granulomatous inflammatory reaction. The common forms of such toxicity include Cocaine abuse, Berryliosis seen in industrial workers, Talcosis (Silicosis) due to talcum powder use, and Tattooing. Cocaine snorting is associated with a peculiar type of drug-induced chronic rhinitis, which leads to inflammation of the sinonasal mucosa, slowly progressing to a destruction of nasal, palatal and pharyngeal tissues. These characteristic lesions due to cocaine abuse are commonly called cocaine-induced midline destructive lesions (CIMDL). Chronic beryllium disease (CBD) is a granulomatous lung disorder that results from beryllium exposure in a genetically susceptible host. Pulmonary talcosis, a form of pulmonary foreign body granulomatosis (PFBG), can occur in drug addicts as a result of intravenous injection of oral medications. The condition has been termed intravascular talcosis, to differentiate it from disorders arising from exposure to inhalational talc, such as simple talcosis, progressive massive fibrosis, talcosilicosis, and talcoasbestosis, often with pleural disease. Skin reactions caused by tattoo (especially red pigment) and silicon needle acupunctures vary from simple dermatitis to lichenoid, pseudolymphomatous and granulomatous reactions. |
