Glycogen metabolism in ischemized organs
| Autor: | L. M. Saburova, L. P. Selivanova |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Muscle tissue
medicine.medical_specialty Kidney Glycogen Ischemia chemistry.chemical_element General Medicine Metabolism Blood flow Biology medicine.disease Iodine General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound medicine.anatomical_structure Endocrinology Biochemistry chemistry Glycogenesis Internal medicine medicine |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 86:1299-1301 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf00800440 |
| Popis: | Acute ischemia was produced by application of a tourniquet to the limb or a clamp to the pedicle of the kidney for a time corresponding to the critical level of metabolism in the test tissue. Restoration of the blood flow in the ischemized kidney led to accumulation of an excess of high-molecular-weight glucose polymer of glycogen type. The character of branching in its molecule, determined from the spectrum of its complexes with iodine, points to changes in processes of glycogen biosynthesis. For the needs of glycogenesis, lactate of the ischemized kidney can be used. It is shown that this abnormal glycogen is actively utilized by kidney tissue. Accumulation of glycogen in muscle tissue after acute ischemia does not exceed the normal level and its structure is unchanged. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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