| Popis: |
Background: Peak expiratory flow (PEF), as an essential index used for screening and monitoring asthma, chronic obstructive pulmonary disease, and respiratory mortality especially in elderly, is recommended especially for low resource settings in low- and middle-income countries. However, few reports have focused on the reference of PEF in China, especially in the middle-aged and elderly. Thus, the aim of this study was to determine age- and sex-specific reference values of PEF in the middle-aged and older Chinese population.Methods: There were 11,717 participants included for reference value analysis and 11,340 participants were included for risk factor analysis. The PEF was measured using a peak flow meter in L/min. The distribution of PEF terciles stratified by sex and age were reported. Multiple linear regression analysis was used to determine the associations between risk factors and PEF.Results: The PEF was higher in men than women across all age subgroups. The value of PEF decreased with age in both men and women. Height, weight, handgrip strength, and household air pollution were positively associated with PEF, and age, waist circumference smoking status were negatively associated with PEF significantly in both men and women (all P Conclusions: Age- and sex-specific centiles of PEF for the middle-aged and older Chinese population were estimated. The reference values for low PEF were provided for epidemiological studies and clinical practice in the future. Interventions on lung function or respiratory disease should be pay more attention on factors associated with PEF. |
