Acute Liver Failure
Autor: | Robert J. Fontana, Erin K. Spengler |
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Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment Encephalopathy Hemodynamics Liver transplantation Gastroenterology law.invention Cerebral edema 03 medical and health sciences 0302 clinical medicine law Internal medicine medicine 030304 developmental biology 0303 health sciences business.industry digestive oral and skin physiology Liver failure medicine.disease Intensive care unit 3. Good health Acetaminophen Etiology 030211 gastroenterology & hepatology business medicine.drug |
DOI: | 10.1016/b978-0-323-47874-8.00002-x |
Popis: | Acute liver failure (ALF) is a rare but dramatic clinical syndrome associated with high rates of morbidity and mortality. Although there are a multitude of causes of ALF, acetaminophen hepatotoxicity remains the most common cause in the United States. Outcomes in ALF are largely dependent on the etiology, maximal grade of encephalopathy, and management of the infectious, hematologic, hemodynamic, and cerebral complications of ALF in the intensive care unit setting. Liver transplantation is the treatment of choice for patients with a low likelihood of spontaneous survival and is associated with excellent short- and long-term outcomes. |
Databáze: | OpenAIRE |
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