Radiotherapy for Brain Tumors: Current Practice and Future Directions
| Autor: | Albert Murtha, Natalie Logie, Adeleh Duimering, Kim Paulson, Sarah Baker |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Cancer Research medicine.medical_specialty business.industry medicine.medical_treatment Radiation therapy 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Oncology Current practice 030220 oncology & carcinogenesis Molecular Medicine Medicine Medical physics business |
| Zdroj: | Current Cancer Therapy Reviews. 16:182-195 |
| ISSN: | 1573-3947 |
| Popis: | Radiotherapy is an important component of the treatment for primary and metastatic brain tumors. Due to the close proximity of critical structures and normal brain parenchyma, Central Nervous System (CNS) radiotherapy is associated with adverse effects such as neurocognitive deficits, which must be weighed against the benefit of improved tumor control. Advanced radiotherapy technology may help to mitigate toxicity risks, although there is a paucity of high-level evidence to support its use. Recent advances have been made in the treatment for gliomas, meningiomas, benign tumors, and metastases, although outcomes remain poor for many high grade tumors. This review highlights recent developments in CNS radiotherapy, discusses common treatment toxicities, critically reviews advanced radiotherapy technologies, and highlights promising treatment strategies to improve clinical outcomes in the future. |
| Databáze: | OpenAIRE |
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