Protective effect of hypothermia on brain neurons in rats exposed to ionizing radiation
| Autor: | R. Ya. Gordon, V. V. Rogachevskii, Igor Kraev, S. S. Khutsyan, D. A. Ignat’ev, E. V. Mel’nikova |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Endoplasmic reticulum Biophysics Hypothermia Golgi apparatus Biology Microfluorimetry Hippocampal formation law.invention Ionizing radiation symbols.namesake Endocrinology nervous system Biochemistry law Internal medicine medicine symbols medicine.symptom Electron microscope Hypercapnia |
| Zdroj: | Biophysics. 52:344-349 |
| ISSN: | 1555-6654 0006-3509 |
| DOI: | 10.1134/s0006350907030165 |
| Popis: | The protein-synthesizing system of hippocampal (CA1, CA3) and sensorimotor cortex neurons is damaged less and recovers much quicker in rats exposed to 8 Gy of γ-radiation under hypoxia/hypercapnia (body temperature 16–18°C) than under usual conditions, as evidenced by microfluorimetry and electron microscopy. The radioprotective effect does not cover the membrane structures (endoplasmic reticulum and Golgi complex), and their restoration is not so prompt. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink