FRACTIONATED DOSING OF CYCLOPHOSPHAMIDE FOR ESTABLISHING LONG-LASTING SKIN ALLOGRAFT SURVIVAL, STABLE MIXED CHIMERISM, AND INTRATHYMIC CLONAL DELETION IN MICE PRIMED WITH ALLOGENEIC SPLEEN CELLS1
Autor: | Qi-Wei Zhang, Kikuo Nomoto, Hisataka Yasui, Yukihiro Tomita, Hisanori Mayumi, Masayoshi Umesue |
---|---|
Rok vydání: | 1997 |
Předmět: | |
Zdroj: | Transplantation. 63:1667-1673 |
ISSN: | 0041-1337 |
Popis: | Background.Injection of allo-spleen cells (SC) followed by a single dose of cyclophosphamide (CP) can induce tolerance of tumor and/or skin allografts in mice. To minimize the damage caused by CP, fractionation of CP that can establish long-lasting skin graft survival, stable mixed chimerism, and in |
Databáze: | OpenAIRE |
Externí odkaz: |