FRACTIONATED DOSING OF CYCLOPHOSPHAMIDE FOR ESTABLISHING LONG-LASTING SKIN ALLOGRAFT SURVIVAL, STABLE MIXED CHIMERISM, AND INTRATHYMIC CLONAL DELETION IN MICE PRIMED WITH ALLOGENEIC SPLEEN CELLS1

Autor: Qi-Wei Zhang, Kikuo Nomoto, Hisataka Yasui, Yukihiro Tomita, Hisanori Mayumi, Masayoshi Umesue
Rok vydání: 1997
Předmět:
Zdroj: Transplantation. 63:1667-1673
ISSN: 0041-1337
Popis: Background.Injection of allo-spleen cells (SC) followed by a single dose of cyclophosphamide (CP) can induce tolerance of tumor and/or skin allografts in mice. To minimize the damage caused by CP, fractionation of CP that can establish long-lasting skin graft survival, stable mixed chimerism, and in
Databáze: OpenAIRE