1H NMR and IR spectra of antitumour anthracyclines: Effect of the substitution pattern on the chemical shift values of the phenolic protons and on IR absorptions of the quinone system

Autor:	Elena Gandini, Sergio Penco, Aristide Vigevani, Marzia Ballabio
Rok vydání:	1985
Předmět:	Anthracycline Antibiotics Daunorubicin Chemistry Stereochemistry Infrared spectroscopy General Chemistry Medicinal chemistry Quinone medicine Proton NMR Molecule General Materials Science Doxorubicin Clinical treatment medicine.drug
Zdroj:	Magnetic Resonance in Chemistry. 23:344-352
ISSN:	1097-458X 0749-1581
Popis:	1H NMR and IR data of numerous natural and synthetic analogues of daunorubicin and doxorubicin, anthracycline antibiotics successfully used in the clinical treatment of human tumours, have been recorded. The chemical shift values of the phenolic protons of approximately 130 compounds are reviewed and discussed with the aim of establishing a relationship between δ values and structural features. The IR absorptions of the quinone system in the region 1560–1680 cm−1 are also examined.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::88ad0584ef2e67b66518bff1aed86cdd https://doi.org/10.1002/mrc.1260230513 Zobrazit plný text záznamu Plný text