Coupling Chromatography and Crystallization for Efficient Separations of Isomers

Autor: Wolfgang Beckmann, Andreas Seidel-Morgenstern, Heike Lorenz, D. Sapoundjiev, Andreas Brandt, K. Gedicke, Uwe Budde
Rok vydání: 2005
Předmět:
Zdroj: Adsorption. 11:591-596
ISSN: 1572-8757
0929-5607
DOI: 10.1007/s10450-005-5990-8
Popis: Within the pharmaceutical industry and in biotechnology there is an increasing need for selective and efficient separation technologies to isolate and purify value-added products. A hybrid process approach combining chromatography and fractional crystallization is studied below. The work presented is concerned with the application and evaluation of this concept in order to isolate a certain pharmaceutical intermediate from a binary mixture. A comparison with performing the same separation exclusively in a single chromatographic process is given also.
Databáze: OpenAIRE