Coupling Chromatography and Crystallization for Efficient Separations of Isomers
Autor: | Wolfgang Beckmann, Andreas Seidel-Morgenstern, Heike Lorenz, D. Sapoundjiev, Andreas Brandt, K. Gedicke, Uwe Budde |
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Rok vydání: | 2005 |
Předmět: | |
Zdroj: | Adsorption. 11:591-596 |
ISSN: | 1572-8757 0929-5607 |
DOI: | 10.1007/s10450-005-5990-8 |
Popis: | Within the pharmaceutical industry and in biotechnology there is an increasing need for selective and efficient separation technologies to isolate and purify value-added products. A hybrid process approach combining chromatography and fractional crystallization is studied below. The work presented is concerned with the application and evaluation of this concept in order to isolate a certain pharmaceutical intermediate from a binary mixture. A comparison with performing the same separation exclusively in a single chromatographic process is given also. |
Databáze: | OpenAIRE |
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