Drugs affecting coagulation

Autor: James Barrowman, Ming Wilson
Rok vydání: 2021
Předmět:
Zdroj: Anaesthesia & Intensive Care Medicine. 22:729-737
ISSN: 1472-0299
DOI: 10.1016/j.mpaic.2021.07.024
Popis: The clotting cascade is a complex process and is an important survival mechanism. Major haemorrhage and thromboembolic events remain major causes of increased morbidity and mortality. Drugs affecting coagulation have primarily been utilized to treat or reduce the risk of thromboembolic events. However, the recent progress in the management of major trauma and treating coagulopathy has resulted in further research and development of drugs that improve clotting function. Knowledge of drugs used for both clinical circumstances is now required when working in anaesthesia or intensive care.
Databáze: OpenAIRE