A photocleavable stabilizer for the preparation of PHEMA nanogels by dispersion polymerization in supercritical carbon dioxide
| Autor: | Christine C. Dupont-Gillain, Christophe Detrembleur, Michel J. Genet, Yasmine Adriaensen, Chandrasekar Kuppan, Bruno Grignard, Christine Jérôme, David Alaimo, Charles-André Fustin, Jean-François Gohy |
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| Rok vydání: | 2017 |
| Předmět: |
Dispersion polymerization
Acrylate Supercritical carbon dioxide Materials science Polymers and Plastics Organic Chemistry Radical polymerization Bioengineering 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Methacrylate 01 natural sciences Biochemistry 0104 chemical sciences chemistry.chemical_compound chemistry Polymer chemistry Copolymer Reversible addition−fragmentation chain-transfer polymerization 0210 nano-technology Nanogel |
| Zdroj: | Polymer Chemistry. 8:581-591 |
| ISSN: | 1759-9962 1759-9954 |
| Popis: | A new photo-sensitive diblock copolymer composed of a hydrophilic sequence of poly(ethylene oxide) (PEO) linked to a CO2-philic sequence of poly(1H,1H,2H,2H-heptadecafluorodecyl acrylate) (PFDA) by a light sensitive o-nitrobenzyl group was successfully synthesized by RAFT polymerization and used as a stabilizer for the free radical polymerization of 2-hydroxyethyl methacrylate (HEMA) dispersion in α,α,α-trifluorotoluene and supercritical carbon dioxide (scCO2). Thanks to this fluorinated stabilizer, well-defined particles of PHEMA down to 350 nm diameter were produced in scCO2. Advantageously, the photocleavable group at the block junction of the stabilizer could be cleaved by exposing the particles to UV light so that the fluorinated block could be extracted in TFT or scCO2. As supported by X-ray photoelectron spectroscopy (XPS) analysis, up to 80% of the fluorinated block of the stabilizer can be removed, leading to efficient swelling and dispersion of the resulting PHEMA nanogels in water. |
| Databáze: | OpenAIRE |
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