A Comparative Analysis of Clinical Characteristics and Laboratory Findings of COVID-19 between Intensive Care Unit and Non-Intensive Care Unit Pediatric Patients: A Multicenter, Retrospective, Observational Study from Iranian Network for Research in Viral Diseases (INRVD)

Autor: Alireza Fahimzad, Iraj Sedighi, Neda Pak, Mitra Khalili, Mohammad Farahmand, Mohammad Reza Shokrollahi, Hosein Heydari, Zahra Movahedi, Anahita Sanaei Dashti, Fatemeh Cheraghali, Ahmad Shamsizadeh, Mohammadreza Mirkarimi, Mohsen Alisamir, Houman Hashemian, Jafar Soltani, Ali Hosseininasab, Abdolkarim Hamedi, Mohammad Sadegh Rezai, Shirin Sayyahfar, Manijeh Kahbazi, Aliakbar Abedini, Afsaneh Akhondzadeh, Hamid Reza Sherkatolabbasieh, Ali Akbar Razlansari, Mina Alibeik, Soheil Omid Malayeri, Zohreh Shalchi, Ali Shahabinezhad, Parinaz Khalkhali Asl, Fatemeh Nafe Monfared, Shiva Maleki, Rezvan Kakavand, Babak Shahbaz, Vahdat Poortahmasebi, Sara Akhavan Rezayat, Mohammad Reza Karimi, Ali Jafarpour, Saber Soltani, Azam Ghaziasadi, Razieh Dowran, Shohreh Azimi, Shima Sadeghipour Marvi, Foad Abazari, Milad Zandi, Delaram Yaghoobzadeh, Seyed Mohammad Jazayeri, Ahmad Tavakoli
Rok vydání: 2021
DOI: 10.21203/rs.3.rs-326352/v1
Popis: Background: To date, less is known about the clinical features of COVID-19 pediatric patients admitting to ICUs. Herein, we aimed to describe the differences in demographic characteristics, laboratory findings, clinical presentations, and outcomes between COVID-19 pediatric patients admitting to ICU and non-ICU settings.Methods: This multicenter study involved 15 general and pediatrics hospitals on confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by positive real-time reverse transcription polymerase chain reaction (RT-PCR) between March 19 and May 31, 2020, during the initial peak of the COVID-19 pandemic in Iran.Results: Overall, 166 patients were included, of which 61 (36.7%) required ICU admission, especially in PConclusions: Underlying diseases were the major contributing factors in COVID-19 pediatric patients for the increased ICU admissions and mortality rates. There are few paraclinical parameters for differentiating pediatrics in terms of prognosis and serious outcomes of COVID-19. Healthcare providers should consider children as a high-risk group, especially those with younger age and underlying medical conditions and define strategies to control and prevent COVID-19 transmission in this population.
Databáze: OpenAIRE