Recent Observations Concerning the Relationship of Blood Lead to Erythrocytic Protoporphyrin

Autor:	R. L. Bornschein, P. A. Succop, P. B. Hammond, S. B. Roda, R. D. Greenland
Rok vydání:	1989
Předmět:	Adenosine triphosphatase medicine.medical_specialty medicine.diagnostic_test business.industry Zinc protoporphyrin Rate of increase chemistry.chemical_compound Endocrinology chemistry Internal medicine Lead exposure Medicine Protoporphyrin Blood lead level Lead (electronics) business
Zdroj:	Lead Exposure and Child Development ISBN: 9789401068680
DOI:	10.1007/978-94-009-0847-5_33
Popis:	Blood lead concentration (PbB) and erythrocytic protoporphyrin concentration (EP) are both used as indices of lead exposure in children and in occupationally exposed adults. In a previous study we reported dose- effect and dose-response relationships, in EP vs. PbB (Hammond et al, 1985). In the present study we report the influence of age on the threshold for an EP response to PbB, as well as on the slope of the dose-effect interaction. In the age range 12–30 months the threshold for effect of PbB on EP falls progressively, while the magnitude of the dose-effect increases with age. The rate of decline in the threshold for In EP and the rate of increase for ln EP·PbB-1 are linearly related to age.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::885d4ff38ae67db48016ebda0b114962 https://doi.org/10.1007/978-94-009-0847-5_33 Zobrazit plný text záznamu