Synthesis, Characterization and Antimicrobial Activities of New Mixed Ligand Complexes of Copper(II) with 1,10-Phenanthroline and Thymine

Autor:	Yosef Bayeh, Wolfgang Linert, Madhu Thomas, Atakilt Abebe
Rok vydání:	2019
Předmět:	biology Chemistry Klebsiella pneumoniae Phenanthroline biology.organism_classification medicine.disease_cause Antimicrobial Thymine Solvent chemistry.chemical_compound Staphylococcus aureus medicine Escherichia coli Shigella boydii Nuclear chemistry
Zdroj:	Journal of Transition Metal Complexes. 2:1-6
ISSN:	2566-0144 2566-0136
Popis:	A novel mixed ligand complexes having the formulae [Cu(L1)2(H2O)2]Cl2 and [Cu(L1)2L2H2O]Cl (L1 = 1,10-phenanthroline, L2 = thymine) have been prepared and characterized by various physicochemical studies such as elemental analysis, molar conductance in nonaqueous solvent, infrared and electronic spectra. Both the ligands as well as the metal complexes were used further to investigate the biological activities (antibacterial) against Staphylococcus aureus (SA) (ATCC 25923), Streptococcus pneumonia (SP) (clinical isolate), methicillin-resistant Staphylococcus aureus (MRSA) (clinical isolate), Klebsiella pneumoniae (KP) (clinical isolate), Escherichia coli (EC) (clinical isolate), and Shigella boydii (SBD) (ATCC 12022). On comparing the biological activities, the complexes showed enhanced antimicrobial activity compared to the free metal salt with thymine being lower than that of 1,10-phenanthroline.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::884f89c5f2f08a4abcf9f5e033474c86 https://doi.org/10.32371/jtmc/236072 Zobrazit plný text záznamu