Characterization of drug responses of the intestine of the house musk shrew (Suncus murinus)
| Autor: | Furukawa Kyoko, Irie Kaoru, Nomoto Teruko, Muraki Takamura, Uchida Yoko, Fujii Emiko |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Pharmacology
medicine.medical_specialty Immunology Thyrotropin-releasing hormone Biological activity Suncus Biology biology.organism_classification Norepinephrine chemistry.chemical_compound Endocrinology chemistry Internal medicine medicine Autacoid Neurotransmitter Histamine Acetylcholine medicine.drug |
| Zdroj: | Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 91:613-617 |
| ISSN: | 0306-4492 |
| DOI: | 10.1016/0742-8413(88)90087-4 |
| Popis: | 1. 1. To characterize the pharmacological properties of the intestine of Suncus murinus , an Insectivora, the effects of drugs on the mechanical activity of the isolated intestine were examined. 2. 2. The drugs examined include: (1) autonomie drugs such as acetylcholine, nicotine, norepinephrine, epinephrine and isoproterenol; (2) autacoids such as histamine and 5-hydroxytryptamine; (3) peptides such as bradykinin, thyrotropin releasing hormone and methionine-enkephalin. 3. 3. The present study shows that the pharmacological responses of the intestine of Suncus murinus , especially to isoproterenol, histamine and peptides, have some properties distinct from those of rodents. |
| Databáze: | OpenAIRE |
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