Acute effects of tartrazine (E102) exposure on behavior, and histology of land snail Helix aspersa biological model
| Autor: | Smina Ait Hamlet, Houria Berrebbah, Samira Bensoltane |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Acute effects Biological modeling Helix (gastropod) fungi Land snail Histology 04 agricultural and veterinary sciences Biology biology.organism_classification 040401 food science 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology 0404 agricultural biotechnology Biochemistry chemistry Tartrazine |
| Zdroj: | Nutrition & Santé. :43-51 |
| ISSN: | 2353-026X 2253-0983 |
| Popis: | Introduction. Tartrazine is an azofood additive widely used in the pharmaceu-cal, cosmetic, food, and other industries. Objective. To assess the effects of tartrazineon the attitude to move and to eat, and histological changes in digestive, and renal sys-tem, after an acute treatment on a biological model the snail Helix aspersa. Material and Methods. Snails were exposed orally, and by contact to flour contaminated with this dye for 24 hours. Adult snails were divided into two groups of 20 animals each. The control group fed flour alone. The experimental group was administered orally with flour treated with tartrazine (200mg/g flour). Results. The observation of behaviour revealed inhibitory effects of tartrazine on locomotion, and nutrition of snails. Histolo-gical examination of intestines, hepatopancreas, and kidney of treated animals showed altered tissue structures, with advanced degeneration of digestive tubules, connective tissue, and smooth muscle fibers of the walls surrounding the three organs, in response to tartrazine, compared to controls. Conclusion. This study suggests that acute exposure to tartrazine may lead to disorders in locomotor, and nutritional behavior, in addition to tissue alterations. Therefore, this study on behavior, supported by histological changes in H. Aspersa can be used as potential biomarkers of exposure to other azodyes. |
| Databáze: | OpenAIRE |
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