| Popis: |
A simple, rapid and sensitive method of electrophoresis is described using Cellogel R.S. “wedge strips” to study cerebrospinal fluids. This support medium is able to produce multifractionation of C.S.F, proteins, particularly γ-globulins, this having great significance with regard to subacute sclerosing panencephalitis (S.S.P.E.) and multiple sclerosis. Forty six C.S.F, samples from African people have been studied using this method, after concentration of the samples by vacuum dialysis. The normal African group showed similar results to those of the Europeans, but γ-globulins, which represented 17.3% of total proteins, were significantly higher than in the case of European people. In 10 cases of S.S.P.E., electrophoresis using Cellogel R.S. “wedge strips” showed in all cases in the slow γ-globulin area, several (2 to 7) subtle and deep bands, with constant mobilities, which seem to be the C.S.F, symptom of this disease. |
