A novel synthesis of 2,3-dihydro-7(1H)-indolizinones

Autor:	David Gravestock, Ian G. Peirson
Rok vydání:	2000
Předmět:	Silver nitrate chemistry.chemical_compound chemistry Intramolecular force Organic Chemistry Drug Discovery Acetonitrile Biochemistry Medicinal chemistry Coupling reaction Catecholborane
Zdroj:	Tetrahedron Letters. 41:3497-3500
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)00406-8
Popis:	Intramolecular coupling reactions of enynes 2-[1-(2-propynyl)tetrahydro-2H-pyrrol-2-ylidene]acetonitrile (10) and ethyl 2-[1-(2-propynyl)tetrahydro-2H-pyrrol-2-ylidene]acetate (11), using 9-BBN, catecholborane and alkaline silver nitrate, afforded the 2,3-dihydro-7(1H)-indolizinones, 7-oxo-1,2,3,7-tetrahydro-8-indolizinecarbonitrile (5) and ethyl 7-oxo-1,2,3,7-tetrahydro-8-indolizinecarboxylate (6), respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8842b6a566efbbc27d90d99bd1d52063 https://doi.org/10.1016/s0040-4039(00)00406-8 Zobrazit plný text záznamu Full Text from ScienceDirect